Compounds | IC50 | ||
---|---|---|---|
CYP2B4 | CYP2B5 | CYP2B1 | |
μM | |||
1-Phenylimidazole | 0.90 | 4.2 | 0.59 |
1-(4-Chlorophenyl)imidazole | 0.12 | 15.6 | 0.08 |
4-Phenylimidazole | 0.49 | 8.4 | 0.26 |
4-(4-Chlorophenyl)imidazole | 0.04 | 3.8 | 0.07 |
Values are the means of two independent experiments performed in duplicate and conducted as described under Experimental Procedures. Data for CYP2B4 and 2B1 are determined by BROD assay. Data for CYP2B5 are determined by PROD assay.