Table 1

Peptide primary structure and identification

PeptideSequence1-aESMS (m/z)Amino Acid Analysis1-b
PMBN TXcyclo[XXFLXXT] 963.6  (962.6)T,1.92;  X,4.98;  L,1.0;  F,1.0
[Phe6]PMBN TXcyclo[XXFFXXT] 998.0  (997.1)T,1.89;  X,4.95;  F,2.0
[Ala6]PMBN TXcyclo[XXFAXXT] 921.9  (920.2)T,1.93;  X,5.09;  A,1.0;  F,1.0
[d-Trp5]PMBN TXcyclo[XXWLXXT] 1002.6  (1001.4)T,1.78;  X,4.88;  L,1.0
[d-Tyr5]PMBN TXcyclo[XXYLXXT] 979.4  (978.6)T,1.71;  X,4.67;  L,1.0;  Y,1.0

  • ESMS, electrospray ionization mass spectrometry.

  • ↵1-a D-amino acid are in boldface. X = Dab.

  • ↵1-b Trp destroyed upon hydrolysis procedure.