Table 2

Desensitization of GRK2-antisense clones

Cell ClonesHalf-Maximal Desensitization Time
min
U-93711.7  ±  1.6  (4)
D211.8  ±  1.5  (3)
A240.8  ±  5.3  (3)2-150
D551.7  ±  5.3  (3)2-150
H310.5  ±  1.2  (3)

The apparent rate of desensitization was calculated from the data in Fig. 5A using the equation for monoexponential decay. The table shows the mean ± S.E.M.; the number of determinations (n) is in parentheses. The apparent rates of desensitization were compared with U-937 using an unpaired t test, and the D5 and A2 clones were found to be significantly different.

    • 2-150 , p < 0.01.