Calculated IC50 values for MDA468 NQ-16 and HCT116 cell lines
IC50 values are the average of a minimum of three separate measurements ± S.E.M.
| Compound | IC50 | |
|---|---|---|
| MDA468 NQ-16 | HCT116 | |
| nM | ||
| ES936 | 732 ± 49 | 569 ± 48 |
| Streptonigrin | 2.2 ± 0.06 | 6.7 ± 1 |
| Streptonigrin + 100 nM ES936 pretreatment | 13 ± 0.4* | 11 ± 0.6* |
↵* Significant difference (two-sample t test, α = 0.05) from values obtained without ES936 pretreatment.