TABLE 1

Binding data

Without Galantamine With Galantamine
BmaxKdBmaxKd
fmol / mg protein nM fmol / mg protein nM
[3H]Nicotine 37.6 ± 6.05 10.3 ± 4.4 39.0 ± 5.5 12.8 ± 4.6
[3H]Epibatidine 48.5 ± 12.8 0.31 ± 0.05 45.5 ± 7.9 0.22 ± 0.02
[3H]MLA 48.8 ± 6.4 1.07 ± 0.31 43.5 ± 4.4 0.95 ± 0.19