IC50 | 95% Confidence Interval | Ratioa | |
---|---|---|---|
nM | |||
α2β2 | >10,000 | >62,500 | |
α2β4 | >10,000 | >62,500 | |
α3β2 | 8.72 | 6.84-11.1 | 54.5 |
α3β4 | 2100 | 1330-3310 | 13,100 |
α4β4 | >10,000 | >62,500 | |
α6/α3β2 | 0.154 | 0.134-0.178 | 0.962 |
α6/α3β2β3 | 0.160 | 0.135-0.189 | 1.00 |
α6/α3β4 | 6.44 | 4.33-9.57 | 40.3 |
α7 | 1051 | (731-1510) | 6,570 |
↵ a nAChR subtype IC50/α6/α3β2β3 IC50