Comparison of 12.5 mg/kg/day × 18 days oral BaP effects on bone marrow of Cyp1a1(−/−) versus Cyp1a1(+/+) mice
Each group contains six mice. Note the same control values in this table are also listed in the previous table.
| Cyp1a1(−/−) | Cyp1a1(+/+) | |||
|---|---|---|---|---|
| BaP | Control | BaP | Control | |
| % | ||||
| Neutrophils | 40.2 ± 1.4 | 29.3 ± 5.2 | 28.2 ± 3.3 | 26.4 ± 3.1 |
| P = 0.04a | ||||
| P = 0.012b | ||||
| P = 0.026c | ||||
| Eosinophils | 3.29 ± 1.2 | 2.6 ± 0.3 | 3.63 ± 0.88 | 3.0 ± 1.0 |
| Total lymphocytes | 18.2 ± 2.7 | 14.2 ± 2.5 | 18.9 ± 1.9 | 15.0 ± 3.3 |
| Total erythroid | 27.4 ± 2.7 | 37.6 ± 2.6 | 31.8 ± 3.4 | 38.3 ± 2.6 |
| P = 0.022a | ||||
| P = 0.01b | ||||
| Total myeloid | 48.5 ± 0.86 | 43.7 ± 4.3 | 36.0 ± 3.1 | 42.0 ± 3.6 |
| P = 0.01c | ||||