Description of the data set used to build the HMMs used for mining and classification into the 15 main families of GPCRs in the genomes investigated

The source of the dataset is indicated in parentheses.

Model Name Number of GPCRs Description
ADHSEC 46 13 human secretin-like GPCRs (Fredriksson et al., 2003c); 33 adhesion-like GPCRs (Fredriksson et al., 2002, 2003a,b)
CAMP 4 cAMP binding GPCRs from Dictyostelium (
DMODOR 39 D. melanogaster odorant receptors (
FZD 11 Human Frizzled 1-10 and smoothened (Fredriksson et al., 2003c)
GUST 72 Gustatory receptors from A. gambiae (Hill et al., 2002)
GLR 18 8 metabotropic glutamate receptors, 3 taste receptors type 1, 2 GABA receptors, calcium-sensing receptor, 4 orphan GPCRs (Fredriksson et al., 2003c)
MLO 16 Plant GPCRs of the MLO type (Devoto et al., 2003)
NCHM 34 Nematode chemokine receptors (
OA1 2 Ocular albinism genes from mouse and human (Fredriksson et al., 2003c)
RHOD 260 Human Rhodopsin receptors (Fredriksson et al., 2003c)
STE2 4 Yeast pheromone receptors of the STE2 type (
STE3 4 Yeast pheromone receptors of the STE2 type (
TAS2 13 Human taste receptors type 2 (Fredriksson et al., 2003c)
VR 42 Vomeronasal receptors from mouse and rat (