TABLE 2

Comparison of IC50 values of PK1, PK2, and PK2β on PKR1 and PKR2

IC50 values are representative of triplicate experiments in radioligand competition binding assays.

PKR1 PKR2
nM
PK1 27.6 ± 8.2 52.2 ± 16.4
PK2 4.5 ± 0.8 6.4 ± 1.3
PK2β 34.6 ± 13.5 >1000