Data from the elastase driven model time course Data are expressed as -fold difference from time-matched, vehicle-dosed control groups.
| Time after Challenge | ||||
|---|---|---|---|---|
| 2 h | 6 h | 24 h | 48 h | |
| TNFα | 1.2 ± 0.1 | 2.2 ± 0.6 | 2.2 ± 0.8 | 4.5 ± 1.6 |
| IL-1β | 1.4 ± 0.4 | 3.2 ± 0.7 | 3.3 ± 0.9 | 3.3 ± 0.7 |
| MMP-9 | 1.7 ± 0.6 | 1.7 ± 0.5 | 3.2 ± 0.9 | 5.2 ± 1.0 |
| iNOS | 1.9 ± 0.4 | 5.3 ± 2.2 | 4.2 ± 1.3 | 15.0 ± 10.9 |