Effects of AahII on fast activation and inactivation parameters for Nav1.7 and Nav1.3
| Activation | Inactivation | |||||
|---|---|---|---|---|---|---|
| V½ | Slope | n | V½ | Slope | n | |
| mV | mV | |||||
| Na1.7 | ||||||
| Control | −16.3 ± 0.5 | 3.6 ± 0.3 | 4 | −48.4 ± 0.5* | 10.4 ± 0.4 | 4 |
| AahII 50 nM | −18.1 ± 0.5 | 4.1 ± 0.2 | 4 | −43.1 ± 0.4* | 9.2 ± 0.2 | 4 |
| Nav1.3 | ||||||
| Control | −19.6 ± 0.8* | 4.6 ± 0.4 | 4 | −31.6 ± 0.2 | 7.5 ± 0.1 | 4 |
| AahII 50 nM | −28.2 ± 0.9* | 3.2 ± 0.5 | 4 | −32.9 ± 1.6 | 8.2 ± 0.6 | 4 |
↵* P < 0.05