TABLE 1

Comparison of the mouse and human SLC39A14 and SLC39A8 gene structures

All sequences are based on NCBI m37 mouse assembly (Apr 2007; strain C57BL/6J) and NCBI 36 assembly of the human genome (Nov 2005). From the 5′-most (exon 1c) start site to the 3′-most nucleotide of exon 9, the four genes from left to right span 92,502, 57,942 [?], 64,860, and 88,148 bp, respectively. For mouse Slc39a14, the genomic 5′ to 3′ sequence is exon 1c, intron 1c, exon 1b, intron 1b, exon 1a, intron 1a, exon 2, intron 2, exon 3, intron 3, exon 4a, intron 4a, exon 4b, intron 4b, exon 5, intron 5,...... exon 9.

Number Mouse Slc39a14 Human SCL39A14 Mouse Slc39a8 Human SLC39A8
Exon Intron Exon Intron Exon Intron Exon Intron
bp bp bp bp
1c 139 32,340 [?] [?] 256 1486 184 801
1b 110 29,383 [?] [?] 146 632 139 429
1a 131 15,130 104 37,287 37 156 26 159
2 279 2037 285 3329 451 22,325 748 28,613
3 187 604 187 1449 163 6725 163 8062
4(a) 170 4688 170 4664 170 1409 170 2324
4(b) 170 2625 170 2573
5 120 584 123 866 123 465 123 507
6 189 117 189 115 171 25,955 165 36,237
7 208 923 208 1370 208 197 208 197
8 185 1837 185 1716 185 2018 185 4296
9 516 3122 1582 1527
Totala 1993a 90,268 [4573 bp] [53,369 bp] 3309 61,368 bp 3473 84,510
1964 3199 3428
1985 3090 3315
  • [?], not detected in the human genome.

  • a The three total lengths of exons denote the mRNA transcripts using exons 1c, 1b, or 1a, respectively (which are found in the dbEST database).