TABLE 1

IC50 values for erlotinib, STAT3 decoy, and gossypol in SCCHN cell lines

UM-22B, PCI-15B, and 1483 cells were treated with a range of concentrations of erlotinib, STAT3 decoy, or gossypol for 72 h. MTT assays were then performed, and IC50 values were calculated. The experiment was performed three times with similar results.


Cell Line

Erlotinib

Decoy

Gossypol
μM nM μM
UM-22B 10 12.6 2.669
PCI-15B 0.33 38.3 2.968
1483
7
2.05
2.135