Fit values for Z
Shown are the data for potentiation of responses to low concentrations of GABA and for responses to 1 mM P4S. Each column shows the fit value for Z ± S.E. of the fit, the number of data pairs fit in parentheses, and the inverse of Z, which gives the slowing of the closing process. 3α5βPOH consistently reduced responses to low concentrations of GABA for oocytes injected with βαW γβαW concatemers (Table 2).
Construct | GABA + 1 μM 3α5αPOH | GABA + 1 μM 3α5βPOH | GABA + 1 μM 3α5αP | 1 mM P4S + 1 μM 3α5αPOH |
---|---|---|---|---|
βα γβα | 0.16 ± 0.02 (40) 6.2× | 0.23 ± 0.03 (7) 4.3× | 0.10 ± 0.01 (23) 9.9× | 0.08 ± 0.01 (6) 12.3× |
βα γβαL | 0.16 ± 0.02 (24) 6.3× | 0.27 ± 0.03 (6) 3.8× | 0.13 ± 0.02 (6) 7.7× | 0.14 ± 0.02 (6) 7.4× |
βαL γβα | 0.30 ± 0.02 (19) 3.3× | 0.46 ± 0.02 (5) 2.2× | 0.26 ± 0.02 (6) 3.8× | 0.22 ± 0.03 (6) 4.6× |
βαL γβαL | 0.92 ± 0.04 (20) 1.1× | 0.95 ± 0.08 (7) 1.1× | 0.90 ± 0.06 (6) 1.1× | 0.75 ± 0.10 (7) 1.3× |
βα γβαW | 0.34 ± 0.04 (16) 2.9× | 0.53 ± 0.04 (7) 1.9× | — | 0.32 ± 0.03 (6) 3.1× |
βαW γβα | 0.46 ± 0.02 (17) 2.2× | 0.65 ± 0.02 (8) 1.5× | — | 0.56 ± 0.03 (7) 1.8× |
βαW γβαW | 1.01 ± 0.04 (21) 1.0× | — | — | 0.99 ± 0.03 (11) 1.0× |
—, not applicable.