Fitted curve parameters of β-arrestin recruitment to CXCR7
Summary of the analyses of CXCL12-induced recruitment of β-arrestin to CXCR7 (n = 4). The difference of logEC50 in presence and absence of AMD3100 of the curves is statistically significant. In addition, simultaneous curve fitting for each set of curves (±AMD3100) confirmed the statistical significance for the difference between the curves in three out of four experiments (P < 0.05). Values are presented as mean ± S.E.M.
Ligands | EC50 | logEC50 | n |
|---|---|---|---|
| M | |||
| CXCL12 | 1.18 × 10−8 | −8.01 ± 0.16 | 4 |
| CXCL12 + AMD3100 | 6.48 × 10−9 | −8.30 ± 0.19* | 4 |
↵* Paired t test, P = 0.0049.