TABLE 1

Human miRNAs that might target ABCG2 3′-UTR

Listed are the top 10 candidates predicted by PITA algorithm concerning target-site accessibility. Note that hsa-miR-328 exhibits the lowest dGduplex value, as well as the lowest ddG.


microRNA

Position

dGduplex

dGopen

ddG
kcal/mol
hsa-miR-328 618 −31.3 −17.5 −13.8
hsa-miR-134 1106 −19.0 −7.26 −11.7
hsa-miR-520d-3p 43 −21.7 −12.4 −9.29
hsa-miR-146b-5p 1832 −16.6 −8.08 −8.51
hsa-miR-146a 1832 −16.4 −8.08 −8.31
hsa-miR-520e 43 −20.2 −12.4 −7.79
hsa-miR-520f 42 −18.7 −11.6 −7.10
hsa-miR-520c-3p 43 −19.5 −12.4 −7.09
hsa-miR-373 43 −19.1 −12.4 −6.71
hsa-miR-520g
45
−19.9
−13.7
−6.23