Summary of cytotoxic effects of tested compounds
Values are EC50.
| Compound | Cytotoxicity ATP Decrease | Apoptosis Caspase-3 Activation | Necrosis LDH Release |
|---|---|---|---|
| μM | |||
| Staurosporine (Apoptosis) | 15 | 3 | 21 |
| Tamoxifen (Necrosis) | 47 | 4 | 35 |
| LCA | 84 | 65 | 105 |
| CDCA | 650 | 890 | >1000 |
| UDCA | >1000 | N.D. | N.D. |
| CA | >1000 | N.D. | N.D. |
| INT-747 | 230 | 160 | 210 |
| INT-767 | 800 | >1000 | 670 |
N.D., not done.