TABLE 3

Hematological indices of mice treated with vehicle control, Dp44mT, DpC, and gemcitabine after 44 days of treatment

Values are displayed as mean ± S.E.M. (n = 8 mice/group).

Experimental Groups (n = 8)
ControlDp44mT (0.4 mg/kg/day i.v.)DpC (5 mg/kg/day i.v.)Gemcitabine (5 mg/kg/3 days i.p.)
Red blood cells, × 1012/l10.17 ± 0.159.99 ± 0.129.46 ± 0.319.65 ± 0.08
Hemoglobin, g/l146.44 ± 1.68137 ± 1.77**131.88 ± 4.31**147.88 ± 1.19
Hematocrit0.44 ± 0.010.43 ± 0.010.41 ± 0.010.45 ± 0.01
Platelets, × 109/l1042.22 ± 146.571418.63 ± 164.111281.88 ± 159.971060.13 ± 204.75
White blood cells, × 109/l4.53 ± 0.443.15 ± 0.513.5 ± 0.345.51 ± 0.56
Reticulocytes, × 1012/l0.56 ± 0.060.87 ± 0.11*0.77 ± 0.08*0.35 ± 0.12
  • * p < 0.05.

  • ** p < 0.01