TABLE 5

Fold change (FC) 9FC0 and P values for Targretin time-series reverse transcriptase (RT)-polymerase chain reaction (PCR) experiment

The FC and P values for the follow up Targretin time-series RT-PCR experiment are shown. The fold changes are positive for all genes at all time points. The difference compared with controls after 21 days is significant for all genes (P < 0.05). The difference compared with controls after 2.5 days and 7 days is significant for all genes at P < 0.15 and for most genes at P < 0.05 (2.3 days: 9/10; 7 days: 6/10).

2.3 Days Vs. Controls7 Days Vs. Controls21 Days Vs. Controls
Gene SymbolFold ChangeP valueFold ChangeP ValueFold ChangeP value
Abcd32.453.0E-031.451.0E-012.532.4E-03
Acaca2.601.1E-024.624.8E-036.764.4E-04
Acox12.559.4E-031.639.5E-023.343.3E-03
Ech15.564.5E-051.852.5E-023.872.1E-04
Ehhadh7.741.5E-043.902.9E-039.348.4E-05
Ethe12.591.3E-022.701.1E-024.626.8E-04
Fasn2.401.4E-026.992.2E-039.411.6E-04
Por1.841.4E-011.471.1E-011.803.6E-02
Scd13.101.4E-026.271.1E-039.561.1E-04
Srebf11.984.1E-021.791.0E-012.801.4E-02