Down-regulated pathways in confluent cells
The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways with significantly expressed (P < 0.05) genes that were down-regulated in 4 weeks confluent cells, compared with control cells. The percentage of involved genes, compared with total genes, is also shown for every pathway.
| KEGG ID | Pathway | Count | % | P value |
|---|---|---|---|---|
| hsa03010 | Ribosome | 62 | 2.7 | 3.91E-37 |
| hsa03040 | Spliceosome | 60 | 2.6 | 1.11E-22 |
| hsa03018 | RNA degradation | 26 | 1.1 | 1.72E-09 |
| hsa04120 | Ubiquitin mediated proteolysis | 36 | 1.6 | 4.55E-06 |
| hsa03050 | Proteasome | 17 | 0.7 | 2.81E-05 |
| hsa03020 | RNA polymerase | 13 | 0.6 | 4.34E-05 |
| hsa00230 | Purine metabolism | 37 | 1.6 | 4.86E-05 |
| hsa04114 | Oocyte meiosis | 29 | 1.3 | 5.51E-05 |
| hsa04110 | Cell cycle | 31 | 1.3 | 8.77E-05 |
| hsa00970 | Aminoacyl-tRNA biosynthesis | 14 | 0.6 | 7.40E-04 |
| hsa00240 | Pyrimidine metabolism | 23 | 1.0 | 1.76E-03 |
| hsa03022 | Basal transcription factors | 12 | 0.5 | 2.03E-03 |
| hsa03410 | Base excision repair | 10 | 0.4 | 1.70E-02 |
| hsa00030 | Pentose phosphate pathway | 8 | 0.3 | 2.51E-02 |
| hsa00450 | Selenoamino acid metabolism | 8 | 0.3 | 3.09E-02 |