Summary of signaling and LGR4 ECD binding data for RSPO4 proteins produced in different expression systems
Emax values are % of bacterially produced MBP-Th-RSPO4. The number of observations is indicated in parentheses.
↵a Fu1-Fu2 domain module.
↵b Full-length protein.
↵** P < 0.01 versus bacterially produced MBP-Th-RSPO4 by unpaired t test.