TABLE 1

Macrophage viability after exposure to gedunin

Results are expressed as the percentage of cell viability from quadruplicate wells (2 × 105 cell/well), after incubation of macrophages with gedunin from 24 hours (37°C, 5% CO2). Cell viability was assessed by the resazurin reduction method, as described in Materials and Methods.

MediumTween 20 (3%)Gedunin
0.0010.010.11101001000
μM
100 ± 2.902.7 ± 0.05100 ± 1.23100 ± 3.46100 ± 0.22100 ± 1.97100 ± 4.7491.5 ± 3.9686.9 ± 0.39