Effects of perinatal or postnatal chemical treatments on serum T4 levels
| Number of Animals | Free T4 | |
|---|---|---|
| μM | ||
| Control | 15 | 3.0 ± 0.0 |
| Phenytoin | 8 | 1.4 ± 0.4** |
| PTU | 4 | 0.6 ± 0.0** |
| Phenytoin (postnatal) | 7 | 1.6 ± 0.8* |
| Phenytoin (postnatal) + T4 | 6 | 3.3 ± 0.3 |
| Carbamazepine (postnatal) | 4 | 2.4 ± 0.1* |
| PCN (postnatal) | 4 | 1.5 ± 0.2** |
| PHT (through breast milk) | 5 | 2.5 ± 0.2* |
PHT, phenytoin.
↵* P < 0.05; **P < 0.01.