Pharmacological parameters of results shown in Fig. 5, G–I
The results are the mean ± S.E.M. of five independent experiments performed in quadruplicate. Top and bottom are expressed as fold of basal, and log EC50 is expressed as logged EC50 (M).
| ZnCl2 (N = 7) | NiCl2 (N = 5) | NiSO4 (N = 5) | |
|---|---|---|---|
| Top | 4.22 ± 0.20 | 2.99 ± 0.07 | 3.24 ± 0.12 |
| Bottom | 0.95 ± 0.02 | 0.93 ± 0.02 | 0.92 ± 0.02 |
| Log EC50 | −3.42 ± 0.04 | −4.04 ± 0.04 | −3.91 ± 0.06 |
| Hill slope | 2.62 ± 0.57 | 1.75 ± 0.24 | 1.25 ± 0.16 |