Pharmacokinetic Parameter | Compound I (n = 3) | Compound II (n =3) | Efavirenz^{a} (n = 3) |
---|---|---|---|

Dose (mg/kg) | 20 | 20; 100 | 20 |

C_{max} (µg/ml) | 0.54 ± 0.02 | 11.8 ± 0.7; 52.3 ± 5.7 | 1.8 ± 0.6 |

T_{max} (hour) | 4 | 4; 4 | 4 |

AUC_{0–last} (µg/h/ml) | 13.1 ± 0.4 | 201.7 ± 23.4; 896.4 ± 50.71 | 20.4 ± 21.1 |

CL (ml/min/kg) | 25.4 | 1.6; 1.8 | 16.3 |

*T*_{max}, time taken to reach*C*_{max}.↵

Destache et al. (2010).^{a}