TABLE 1

Chemical structures of previously identified inhibitors of RGS Protein family members

Given are compound names and structures of commercially available RGS inhibitors. Compounds with numbers refer to their PubChem identifier, and CCG or UI indicates Center for Chemical Genomics (University of Michigan) or University of Iowa, respectively, nomenclature. Reference is the reference in which the indicated compound was first identified. NEM was included for its reactive nature toward cys residues. Dashes indicate that the structures are cys-reactive probe compounds used in this study.

CompoundStructureRef.CompoundStructureReference
1777233Storaska et al. (2013)CCG-63808Blazer et al. (2010)
1911669Storaska et al. (2013)CCG-55919Roman et al. (2009)
6383479Storaska et al. (2013)CCG-4986Roman et al. (2007)
CCG-50014Roman et al. (2009)1472216Storaska et al. (2013)
CCG-63802Blazer et al. (2010)UI-1590Monroy et al, (2013)
UI-5Monroy et al. (2013)NEM
DACM