TABLE 1 

Slope of the relationship between log(L) and predicted log(EC50)

Results of linear regression of the value for log(EC50) on log(L) (third column), for various values of N (first column) and c (second column). The values were chosen to cover the range of proposed number of sites, and reported values for c for agonists acting on the GABAA receptor. The predictions were fit over a range of values for L that visually appear largely linear, as indicated in the fifth column. The fourth column gives the value of 1/N.

NcSlope1/NRange of L
10.10.421.001–10
10.010.751.001–40
10.0010.861.001–200
20.10.590.501–100
20.010.580.501–1000
20.0010.550.501–1000
30.10.550.331–400
30.010.450.331–2000
30.0010.440.331–2000
40.10.480.251–2000
40.010.390.251–2000
40.0010.390.251–2000
50.10.420.201–1000
50.010.370.201–1000
50.0010.370.201–1000