TABLE 1 

Scotopic ERG amplitudes in RPE65-deficient dogs, pretreatment, and at peak responses postintravitreal administration of the 9-cis-RAL-CM-chitosan conjugate

PretreatmentPosttreatment
Dog 1Dog 2Dog 3 eye 1Dog 4 eye 1Dog 3 eye 2Dog 4 eye 2Dog 1Dog 2Dog 3 eye 1Dog 4 eye 1Dog 3 eye 2Dog 4 eye 2Statistical analysis P
3 cd·s·m−2 a-wave00.500002143.50080.125a
3 cd·s·m−2 b-wave1.21000047.59.519.585.5190.017b
10 cd·s·m−2 a-wave010000359.5926.513.50.031a
10 cd·s·m−2 b-wave1.83.51.502060.517.522.51112.521.50.031a
  • a Failed a Shapiro-Wilk test for normality, a Wilcoxon Signed Rank test was performed.

  • b Passed a Shapiro-Wilk test for normality, a one-tailed paired Student t test was performed.