Selected differentially expressed genes in liver from chow mice and high-fat diet (HFD) mice
Numbers in parentheses indicate gene expression levels quantified as log2 of fold changes.
| Pathways Differentially Regulated in HFD Liver |
|---|
| Lipid metabolism |
| Gpat2 (0.7), Abhd4 (0.6), Acacb (1.2), Acsl5 (0.6), Acsm3 (1.0), Bche (0.7), Echs1 (0.5), Hadh (0.9), Acaca (0.7) |
| TGFb-induced EMT |
| TGFb2 (0.8), Jun (1.7), Fos (1.48), Fosl1 (0.8), Mmp2 (1.0), Edn1 (1.4), Vim (0.8), Ocln (−0.8) |
| Fatty acid metabolism |
| Cd74 (1.5), Elovl5 (1.6), Aacs (2.0), Acaa1b (1.3), Acacb (1.2), Acsf3 (0.7), Acsl5 (0.6), Acsm3 (1.0), Ch25h (1.3), Elovl2 (0.9), Echs1 (0.5), Fads1 (0.8), Fads2 (1.3), Fasn (1.5), Gpam (0.9), Hao2 (3.0), Hadh (0.9), Hsd17b4 (0.5), Myo5a (1.0), Elovl6 (0.9), Acaca (0.7), Scd1 (1.6), Scd2 (1.0), Scd3 (1.5) |
| Arachidonic acid metabolism |
| Cbr3 (1.6), Pla2g6 (0.9), Cyp2c29 (−1.2), Cyp2c37 (−0.8), Cyp2c39 (−0.7), Cyp2c44 (−1.0), Cyp2c50 (−0.7), Cyp2c54 (−1.2), Cyp2c55 (−1.3), Cyp2c70 (−1.6), Cyp4f14 (−0.7) |