Inhibitor | Metformin | MPP | TEA | NBD-MTMA | ASP | |||||
---|---|---|---|---|---|---|---|---|---|---|
IC50 | ±S.E. | IC50 | ±S.E. | IC50 | ±S.E. | IC50 | ±S.E. | IC50 | ±S.E. | |
µM | ||||||||||
Amantadine | 27.1 | 0.7 | 51.0 | 2.2 | 32.1 | 1.5 | 24.5 | 1.6 | 10.1 | 3.8 |
Amitriptyline | 2.4 | 0.7 | 11.3 | 0.4 | 5.0 | 0.6 | 4.0 | 0.6 | 1.8 | 0.1 |
Anastrozole | 51.1 | 0.5 | 327.6 | 2.6 | 113.4 | 9.4 | 86.0 | 6.8 | 39.2 | 3.0 |
Atomoxetine | 6.6 | 0.1 | 20.4 | 2.3 | 12.8 | 2.0 | 7.6 | 0.9 | 3.5 | 0.0 |
Atropine | 1.3 | 0.2 | 12.4 | 0.8 | 3.4 | 0.8 | 2.3 | 0.6 | 1.4 | 0.1 |
Benztropine | 0.4 | 0.0 | 13.4 | 7.2 | 1.0 | 0.1 | 0.8 | 0.2 | 0.3 | 0.0 |
Bupropion | 8.6 | 1.8 | 32.2 | 5.4 | 13.4 | 2.8 | 10.8 | 1.0 | 11.1 | 1.6 |
Buspirone | 10.2 | 0.1 | 68.5 | 4.4 | 19.8 | 1.0 | 19.6 | 3.2 | 8.6 | 2.6 |
Fluoxetine | 18.6 | 1.5 | 56.7 | 4.5 | 36.0 | 5.4 | 20.1 | 2.6 | 16.7 | 0.8 |
Imipramine | 0.4 | 0.2 | 4.9 | 0.3 | 1.3 | 0.3 | 1.4 | 0.1 | 0.5 | 0.3 |
Irinotecan | 3.3 | 0.1 | 15.6 | 1.4 | 4.5 | 0.3 | 3.2 | 0.7 | 1.7 | 0.0 |
Mexiletine | 21.5 | 0.6 | 50.4 | 5.6 | 28.5 | 2.7 | 30.5 | 0.7 | 19.4 | 4.4 |
Naloxone | 29.5 | 0.0 | 235.7 | 9.2 | 67.3 | 2.8 | 55.1 | 6.6 | 20.3 | 3.7 |
Pilocarpine | 34.5 | 0.4 | 109.3 | 12.2 | 61.9 | 0.1 | 48.2 | 1.2 | 55.7 | 24.1 |
Quinidine | 18.6 | 1.6 | 91.1 | 3.4 | 23.6 | 1.0 | 18.7 | 1.2 | 6.4 | 0.3 |
Tacrine | 0.6 | 0.0 | 2.3 | 0.2 | 0.9 | 0.1 | 1.0 | 0.3 | 0.4 | 0.1 |
Trimethoprim | 19.8 | 1.8 | 199.2 | 54.9 | 50.2 | 11.2 | 43.0 | 2.7 | 14.1 | 1.0 |
Tripelennamine | 2.1 | 0.2 | 12.1 | 2.0 | 5.0 | 0.7 | 5.7 | 1.0 | 3.7 | 0.9 |
Tropicamide | 94.3 | 2.4 | 691.5 | 31.3 | 205.4 | 4.6 | 189.0 | 1.6 | 141.4 | 42.5 |
Verapamil | 10.3 | 1.0 | 49.7 | 3.3 | 17.8 | 2.3 | 9.7 | 1.9 | 4.6 | 1.5 |