Calculated IC50 values of selected compounds for the inhibition of 5-LO product biosynthesis in human PMNLs
Values are the mean ± 95% confidence interval from four independent experiments.
| Compound | IC50 (95% CI) |
|---|---|
| μM | |
| Zileuton | 2.07 (1.71–2.51) |
| Baicalein (compound 1) | 11 (8.44–14.33) |
| Quercetin (compound 3) | 5.97 (4.64–7.67) |
| Compound 6 | 2.83 (2.42–3.30) |
CI, confidence interval.