TABLE 4

X-ray data collection and refinement statistics Tubulin-RB3_SLD-TTL complex bound with DJ95 (PDB ID: 6NNG). Values in parentheses indicate the highest-resolution shell.

Data CollectionValue
Space groupP212121
Cell dimensions
 a, b, c (Å)105.42, 157.98, 182.84
 α, β, γ (°)90, 90, 90
 Resolution (Å)50–2.4 (2.44–2.4)
 Rmeas0.092 (0.922)
 I/σ(I)20.89 (2.14)
 Completeness (%)99.2 (99.5)
 Redundancy6.6 (6.4)
Refinement
 Resolution (Å)48.25–2.4 (2.48–2.4)
 Number of reflections117,909 (10,915)
 Rwork/Rfree0.1866/0.2253
 Number of atoms17,724
 Protein16,956
 Ligand/ion215
 Water553
B factors
 Protein49.92
 Ligand/ion52.57
 Water43.07
Root-mean-square deviations
 Bond lengths (Å)0.008
 Bond angles (°)1.05
Ramachandran Plot
 Favored (%)98.04
 Allowed (%)1.91
 Outliers (%)0.05