TABLE 3

EC₅₀ values at TyrA:TyrOMe

Drug	pEC₅₀ (±S.E.)	Hill (±S.E.)	I_max	n
			µA
NS6740	6.838 ± 0.067	1.7 ± 0.37	0.052–1.8	10
NS6740 + PNU-120596	8.445 ± 0.023	3.0 ± 0.41	0.33–35	10

NS6740, 1,4-diazabicyclo[3.2.2]nonan-4-yl(5-(3-(trifluoromethyl)phenyl)furan-2-yl)methanone; PNU-120596, 1-(5-chloro-2,4-dimethoxy-phenyl)-3-(5-methyl-isoxazol-3-yl)-urea.