TABLE 1

Antiproliferative profile of ISL on various cell lines n = 3 for each experiment

Cell LinesTumor TypesIC50
µM
MV4-11Human acute myeloid leukemia3.2 ± 1.2
MOLM-13Human acute myeloid leukemia4.9 ± 2.1
OCI-LY10Human B cell lymphoma20.1 ± 6.7
A549Human lung cancer>50
HGC-27Human gastric cancer>50
HepG2Human hepatocellular carcinoma>50
HCT116Human colorectal cancer>50
MCF-10AHuman mammary epithelial cell>50
Ba/F3Murine pro-B cell line>50