Results of the two-electrode voltage-clamp recording and calcium imaging assay of oligoarginine peptides
Data are presented as IC50 values (95% CIs) (n = 2–6).
| Peptide | IC50 (95% CI) | |||
|---|---|---|---|---|
| Muscle | α3β2 | α9α10 | α7 | |
| μM | ||||
| R3 | >50 | >50 | >50 | >50 |
| WR2 | >50 | >50 | >50 | >50 |
| W2R4 | 1.60 (1.22–2.11) | 1.71 (0.688–4.24) | 7.71 (5.46–10.90) | 1.01 (0.91–1.12) |
| R6 | 19.1 (9.16–40.00) | 7.59 (5.25–10.9) | 0.316 (0.181–0.552) | 4.24 (3.45–5.22) |
| R8 | 7.37 (4.87–11.20) | 20.3 (9.08–45.5) | 0.044 (0.026–0.075) | 11.9 (8.45–16.8) |
| R16 | 0.157 (0.085–0.284) | 2.61 (1.58–4.34) | 0.12 (0.093–0.159) | 3.53 (2.17–5.72) |