Residues within 4 Å of the binding pocket of 2l, epothilone, and paclitaxel
| Molecule | Common residues | Uncommon residues |
|---|---|---|
| Epothilone | β-tubulin residues D223, H226, L227, A230, F269, P271, T273, L360, | β-tubulin residues L214, L272, S274, R275, R281, L283, Y280, Q278, Q279, G276 |
| 2l | β-tubulin residues L214, L216, L272, S274, R275, P357, R358 | |
| Paclitaxel | V22, D25, S233, R358, Q278 |