In vivo exposure after intraperitoneal administration to mice

CD-1 mice were injected intraperitoneally with a single indicated dose. The data shown are mean values from three mice at each time point.

Compound Concentration in Plasma (nM)AUC 0–7 hobs (h·nM)
Compound (dose)30 min2 h4 h7 h
CCG258208 (10 mg/kg)271014402704305970
CCG258747 (10 mg/kg)153011504701704970
  • AUC, area under the curve.