TABLE 2

Kinetic parameters for p-aminobenzoic acid acetylation by NAT1 with variable AcCoA

ConditionVmax (nmol/min per density unit)Km (µM)
Nonacetylated45 ± 2273 ± 17
Acetylated40 ± 4407 ± 58a
  • aP < 0.01 compared with nonacetylated enzyme by Student’s t test with 19 degrees of freedom.