TABLE 1

Analysis of activation of the ρ1 receptor by GABA

The table gives the results of fitting the GABA conc.-Popen response data to eq. 1. The first column shows the constrained value of Popen at 10 μM GABA. The next columns show the calculated value of L and the fitted values of KC and c (best-fit parameter ± S.D.). The number of binding sites for GABA was constrained to 5.

Popen at 10 μM GABALKC (μM)c
0.99910182.11 ± 0.460.085 ± 0.012
0.9810391.73 ± 0.330.097 ± 0.011
0.9610601.44 ± 0.260.110 ± 0.010
0.9410831.24 ± 0.210.119 ± 0.010
0.9211061.09 ± 0.190.128 ± 0.009