Analysis of modulation of the ρ1 receptor by steroids
The table summarizes the results of fitting the steroid conc.-Popen response data from ρ1 wild-type and I307Q mutant receptors to eq. 2. The experiments were conducted in the presence of GABA, and L was calculated as (1−Popen,GABA)/Popen,GABA. The number of binding sites for steroids was constrained to five, and the maximal Popen for GABA was assumed to be 0.999.