Nature of Occupancy-Response Relationship	Generic: Hyperbolic		Limiting Case: Linear
Theoretical expression for transduction coefficient	Division of eq. 1 by eq. 6 and rearrangement of terms gives rise to
Experimental implementation of operational model to determine transduction coefficient	Implementation of the operational model assumes that above equation is valid for experimentally measured values; in other words,
	Since operational model also assumes hyperbolicity, that is the reference agonist can evoke system maximal response, .
	(12)
Experimental determination of transduction coefficient of a test agonist ()	Substituting eqs. 3a, 4a, and 9a		Substituting eqs. 3b, 4b, and 9b
	(13a)		(13b)
Experimental determination of transduction coefficient of a test agonist ()	Equation 12 can be rewritten for reference agonist as
(14)
	Substituting eq. 8a		Substituting eq. 8b
	(15a)		(15b)
Relative experimental transduction coefficient of test agonist with respect to a reference	Relative transduction coefficient, as defined in Kenakin et al. (2012)
	Substituting eqs. 13a and 15a		Substituting eqs. 13b and 15b
	(16a)		(16b)