Ligand | Ligand, μM | AcCYP51, μM | AcCYP51 ligand, μM | Fraction of ligand-bound AcCYP51, % | ||
---|---|---|---|---|---|---|
n1 | n2 | n1 | n2 | |||
Clotrimazole | 20.0 | 5.0 | 0.81 | 0.66 | 16.2 | 13.0 |
Isavuconazole | 20.0 | 5.0 | 0.47 | 0.38 | 9.4 | 7.6 |
31-Norlanosterol | 20.0 | 5.0 | 0.90 | 1.00 | 18.0 | 20.0 |
↵a Experiments were performed in duplicates. Values for the replicates n1 and n2 are shown separately.