TABLE 1

Kinetic parameters of ENT2 and ENT1 knockout cell lines

An unpaired t test was used to determine significance (P < 0.05). All data are represented as mean ± S.D. with n = 3.

ENT1 Uridine UptakeENT2 Uridine UptakeP ValueRatio ENT2:ENT1
Jmax (pmol cm−2 min−1)23.75 ± 0.8844.88 ± 16.340.0891.89
Kt (μM)11.36 ± 3.87156.90 ± 55.600.01613.81