Proteins from GO term T cell receptor signaling pathway whose phosphorylation is regulated by PGE2
The table shows proteins contained in GO term T cell receptor signaling pathway that have one or more phosphosites that are regulated by PGE2 or one of the EP receptor agonists in one or more of the phosphoproteomics studies reviewed here. Commonly used alternative names for the proteins are shown in parenthesis.
| TCR Signaling Protein | Oberprieler | Giansanti | de Graaf | Lone | Conditions Regulated in Lone |
|---|---|---|---|---|---|
| BRAF | ✓ | ||||
| CARD11 (Carma1) | ✓ | ✓ | ✓ | CD8 EP1, EP2, EP3, EP4, PGE2 | |
| CD247 (CD3ζ) | ✓ | ✓ | CD8 EP1, EP2, EP3 | ||
| CD3E | ✓ | ||||
| ELF1 | ✓ | ||||
| FYB1 (ADAP) | ✓ | ✓ | ✓ | CD8 EP2, EP4 | |
| FYN | ✓ | CD8 EP2 | |||
| GATA3 | ✓ | ||||
| LCK | ✓ | ✓ | ✓ | CD8 EP2 CD4 EP1, EP2, EP3, EP4, PGE2 | |
| LCP2 (SLP76) | ✓ | ✓ | CD8 EP2 | ||
| LIME1 | ✓ | CD8 EP1, EP2, EP3, EP4, PGE2 | |||
| MAPK1 | ✓ | ||||
| PLCG1 | ✓ | ✓ | CD8 PGE2 | ||
| PRKD2 | ✓ | ✓ | ✓ | CD4 EP4 | |
| PTPN22 (LYP) | ✓ | ✓ | CD8 EP2 | ||
| PTPRC (CD45) | ✓ | ✓ | CD8 EP2 | ||
| RFTN1 | ✓ | CD8 EP2 | |||
| RNF31 | ✓ | ||||
| SPN (CD43) | ✓ | ✓ | ✓ | CD8 EP1, EP2, EP3, EP4, PGE2 CD4 EP1, EP2, EP3, EP4, PGE2 | |
| TESPA1 | ✓ | CD8 EP2 | |||
| TRAT1 (TRIM) | ✓ | ||||
| WNK1 | ✓ | ✓ | ✓ | CD8 EP2, EP4 |