AMIO (−) | AMIO (−) | AMIO (+) | AMIO (+) | |
---|---|---|---|---|
Slope | Va (mV) | Slope | Va (mV) | |
WT (n = 10) | 4.1 ± 0.4 | −34.4 ± 1.3 | 4.9 ± 0.3 | −36.7 ± 1.6 |
S524Y (n = 6) | 1.9 ± 0.1* | −40.1 ± 1.1 | 2.7 ± 0.2& | −39.7 ± 1.5 |
S1103Y (n = 7) | 6.3 ± 0.4* | −29.6 ± 1.3 | 6.7 ± 0.6 | −33.7 ± 1.6 |
R1193Q (n = 6) | 5.3 ± 0.4 | −33.4 ± 1.7 | 6.2 ± 0.4 | −34.5 ± 2.1 |
V1951L (n = 7) | 4.9 ± 0.5 | −33.9 ± 2.1 | 5.5 ± 0.3 | −33.1 ± 1.7 |