Regular ArticleCharacterization and Functional Analysis of Two Common Human Cytochrome P450 1B1 Variants
References (42)
- et al.
J. Biol. Chem.
(1994) - et al.
J. Biol. Chem.
(1996) - et al.
FEBS Lett.
(1995) - et al.
Am. J. Hum. Genet.
(1998) - et al.
Am. J. Ophthalmol.
(1999) - et al.
J. Biol. Chem.
(1988) J. Biol. Chem.
(1992)- et al.
Biochimie
(1990) Anal. Biochem.
(1976)- et al.
J. Biol. Chem.
(1976)
J. Biol. Chem.
(1964)
J. Biol. Chem.
(1989)
Arch. Biochem. Biophys.
(1996)
Mutat. Res.
(1996)
Arch. Biochem. Biophys.
(1993)
J. Biol. Chem.
(1996)
Carcinogenesis
(1995)
Drug Metab. Dispos.
(1997)
Carcinogenesis
(1997)
Carcinogenesis
(1998)
Cited by (47)
CYP1B1 and hormone-induced cancer
2012, Cancer LettersCitation Excerpt :The SNP 4326C>G, leading to a Leu432Val (L432V) amino acid transition, is associated with an increase in CYP1B1 catalytic activity [65,66], with a subsequent elevation in 4-OH E2 formation resulting in increased oestrogen carcinogenicity [10,64,67]. In contrast, the 142C>G SNP results in an Arg48Gly (R48G) transition giving rise to increased CYP1B1 expression, but without any alterations in catalytic properties [65,68]. Another SNP, 4390A>G, leads to the Asn453Ser (N453S) transition and has been associated with a decrease in protein expression due to increased degradation of the protein [69].
Production of yeast derived microsomal human cyp450 enzymes (sacchrosomes) in high yields, and activities superior to commercially available microsomal enzymes
2019, High Value Fermentation Products, Volume 1: Human HealthCytochrome P450 1B1<sup>∗</sup>2 gene polymorphism in a cturkish population
2019, Fabad Journal of Pharmaceutical Sciences
- 1
To whom correspondence should be addressed. Fax: +46-8-33 73 27. E-mail: [email protected].
Copyright © 2000 Academic Press. All rights reserved.