Special Issue ArticleAspirin Use and Reduced Risk of Gastrointestinal Tract Cancers in the American Cancer Society Prospective Studies
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VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium
2012, Cancer CellCitation Excerpt :Since lymphatics are a conduit for immune cells, it cannot be excluded that VEGF-D-induced dilation of collecting lymphatics may contribute to metastasis by altering the traffic and behavior of immune cells in the SLN, consequently modulating metastatic burden. NSAIDs are commonly used for the treatment of inflammatory disease and can restrict the development of colon cancer (Thun and Heath, 1995; Mantovani et al., 2008; Hirsch et al., 2010) and tumor spread in breast and prostate cancer patients (Holmes et al., 2010; Leitzmann et al., 2002), yet the precise antimetastatic mechanism is unclear. Emerging evidence suggests that COX-2 overexpression and high PGE2 levels are associated with tumor angiogenesis and lymphangiogenesis, processes crucial for metastasis (Iwata et al., 2007; Amano et al., 2003; Tsujii et al., 1998).
Nonsteroidal anti-inflammatory drugs and lung cancer risk: A population-based case control study
2007, Journal of Thoracic OncologyCitation Excerpt :Exposure to NSAIDs during the 5 years before the index date was determined using the detailed TennCare pharmacy file. Because previous studies suggest that cumulative duration of NSAID exposure is important,17,29,30 NSAID exposure-days were determined for each person based on the prescribed days supply. We further classified these exposure-days into four categories (none, <12 months, 12–24 months, 25–60 months).
A trial of adjuvant therapy in colorectal cancer: The VICTOR trial
2003, Clinical Colorectal CancerAspirin and cancer: Report on an American Health Foundation Workshop
1995, Preventive MedicineClinical and histopathological features and prognosis of gastrointestinal adenocarcinomas in jack russell terriers
2021, Journal of Veterinary Medical ScienceImpact of perioperative pain management on cancer recurrence: An ASRA/ESRA special article
2019, Regional Anesthesia and Pain Medicine