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The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins

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  • The ABC of Solute Carriers
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Abstract

The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/). Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

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Authors and Affiliations

  1. Membrane Biology Program and Renal Division, Brigham and Women’s Hospital, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA

    Matthias A. Hediger & Hitomi Takanaga

  2. Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106-4970, USA

    Michael F. Romero

  3. Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA

    Ji-Bin Peng

  4. Harvard Institute of Proteomics, Harvard Medical School, Cambridge, MA 02141, USA

    Andreas Rolfs

  5. HUGO Gene Nomenclature Committee, Department of Biology, University College London, London, NW1 2HE, UK

    Elspeth A. Bruford

Authors
  1. Matthias A. Hediger
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  2. Michael F. Romero
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  3. Ji-Bin Peng
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  4. Andreas Rolfs
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  5. Hitomi Takanaga
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  6. Elspeth A. Bruford
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Correspondence to Matthias A. Hediger.

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Hediger, M.A., Romero, M.F., Peng, JB. et al. The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins. Pflugers Arch - Eur J Physiol 447, 465–468 (2004). https://doi.org/10.1007/s00424-003-1192-y

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  • DOI: https://doi.org/10.1007/s00424-003-1192-y

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