Accumulation of short DNA fragments in hydroxyurea treated mouse L-cells
References (21)
- et al.
Biochem. Biophys. Acta
(1966) - et al.
Virology
(1973) - et al.
Anal. Biochem
(1973) - et al.
Virology
(1968) - et al.
Biochem. Biophys. Acta
(1975) - et al.
Biochem. Biophys. Acta
(1971) - et al.
Cell Tissue Kinet
(1969) - et al.
Cancer Res
(1968) Cancer Res
(1969)- et al.
Eur. J. Biochem
(1971)
There are more references available in the full text version of this article.
Cited by (21)
The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication
2018, Molecular CellCitation Excerpt :Similar to hydroxyurea, emetine uncouples leading strand and lagging strand replication and greatly reduces the overall rate of DNA synthesis. Critically, however, although the residual nascent DNA in hydroxyurea-treated cells is enriched for short Okazaki-like DNA fragments (Laipis and Levine, 1973; Magnusson, 1973a; 1973b; Martin et al., 1977; Radford et al., 1982), the residual nascent DNA in emetine-treated cells results only from leading strand replication (Burhans et al., 1991). Consistent with this, emetine almost completely prevented the appearance of poly(ADP-ribose) in S phase, even in cells in which polymer levels were elevated by incubation with the FEN1 inhibitor.
Suppression of mitotic activity and synchronization of cell development in olfactory epithelium
1986, Developmental Brain ResearchAneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae
1986, Mutation Research - Fundamental and Molecular Mechanisms of MutagenesisThe effect of isoproterenol and hydroxyurea on the presence of ubiquitin and protein A<inf>24</inf> in the rat salivary gland
1982, BBA - Gene Structure and Expression
Copyright © 1977 Published by Elsevier Inc.