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2022, Neurologic ClinicsCitation Excerpt :Caudal brain serotonergic neurons play crucial roles in coordinating control of breathing, arousal, respiratory rhythm generation, blood pressure regulation, thermoregulation, upper airway reflexes, chemosensitivity, and synaptic plasticity. Neuronal activity in these serotonergic neurons in raphe nucleus is highest in wakefulness, reduced in NREM and nearly silent in REM sleep.110 Impaired serotonergic function following nocturnal seizures may predispose to SUDEP.
Copyright © 1979 Published by Elsevier B.V.